170 active substances<\/strong>\u00a0from a range of therapeutic areas were systematically analysed. The dataset includes substances from cardiology, neurology, oncology, metabolic medicine, respiratory medicine, and immunology.<\/p>\n\n\n\nWhy an evidence register is needed <\/strong><\/p>\n\n\n\nSex- and gender-informed medicine is gaining global relevance, as biological differences between patients can influence the effectiveness, safety, and dosing of medicinal products. Despite this growing awareness, research, clinical practice, and regulatory processes often lack a clearly structured, systematically accessible and comparable representation of the information.
\u201cSex-relevant information is currently distributed across different sections of various documents, and the wording varies depending on drug class and document type. A unified structure did not exist. This is exactly where we come in,\u201d explains\u00a0Thao Nguyen<\/strong>, CEO and Founder of EQUAL CARE. \u201cOur newly released, publicly available evidence register creates a technically consistent foundation that allows this information to be identified and compared in a systematic way.\u201d<\/p>\n\n\n\nWhat the analysis of 170 active substances shows <\/strong><\/p>\n\n\n\nDuring the processing of the 170 active substances, different document formats, terminologies, and linguistic patterns were identified. This diversity provided a valuable AI training environment and made it possible to further refine our models for classification, pattern recognition, and semantic structuring, and now to apply this to even larger datasets.<\/p>\n\n\n\n
Through the analysis, these clinical studies can for the first time, be transferred into a unified, machine-readable format. The register does not provide clinical evaluation, risk assessment, or treatment recommendations. Instead, it provides the standard data structure and technical infrastructure required to make existing evidence transparent, comparable, and publicly accessible.<\/p>\n\n\n\n
Why this topic is particularly urgent now\u00a0<\/strong><\/p>\n\n\n\nAlthough sex-related differences in diagnosis, therapy, and tolerability are described in the scientific literature, this information is often difficult to find in everyday clinical practice or is not systematically prepared. Clinical guidelines currently contain only limited sex-specific information, and relevant data points are distributed across numerous documents.<\/p>\n\n\n\n
\u201cMost information important for sex-sensitive medicine already exists, but not in a form that allows systematic analysis,\u201d says Dr. Simone Braun<\/strong>, physician and Founder of EQUAL CARE. \u201cWith the evidence register, we have created for the first time the technical foundation required for data-based comparisons, hypotheses, and further analyses to be built.\u201d<\/p>\n\n\n\nMany additional active substances will be added to the database in the near future. In the longer term, post-marketing data and other high-quality evidence sources will also be incorporated. In this way, a comprehensive and clinically relevant foundation for sex-sensitive diagnostics and therapy will be created step by step.<\/p>\n\n\n\n
Regulatory developments such as the EU AI Act<\/strong> and the European Health Data Space<\/strong> are also increasing the demand for standardised and transparent data structures, EQUAL CARE addresses this gap.<\/p>\n\n\n\nAbout EQUAL CARE <\/strong><\/p>\n\n\n\nEEQUAL CARE is a company founded by\u00a0Thao Nguyen<\/strong>,\u00a0Dr. Simone Braun<\/strong>, and\u00a0Ioana Freise<\/strong>, with locations in Switzerland and Germany. The company develops technical foundations for sex-sensitive healthcare and provides public access to structured, high-quality data. The founders combine expertise in medicine, data analysis, technology, and health regulation and work to make existing medical information structured and transparently accessible. On this basis, EQUAL CARE supports more precise research, digital health solutions, and scientifically grounded, sex-sensitive medicine.
Press Contact
Ioana Freise
Email: mail@equal-care.org
Web: www.equal-care.org<\/p>\n\n\n\n<\/p>\n\n\n\n
German version \/Deutsche Version<\/em><\/p>\n\n\n\nZulassungsstudien von 170 Wirkstoffen nach Geschlechteraspekten analysiert: EQUAL CARE schafft neue Transparenz in der Gesundheitsversorgung <\/strong><\/p>\n\n\n\nZug, 15. Dezember 2025 <\/strong><\/p>\n\n\n\nEQUAL CARE, ein daten- und KI-basiertes Health-Tech-Unternehmen, pr\u00e4sentiert das erste Register, das \u00f6ffentlich verf\u00fcgbare Arzneimittelinformationen strukturiert und nach geschlechtsrelevanten Aspekten durchsuchbar macht. Mit der Analyse der ersten 170 Wirkstoffe (INNs) <\/strong>erreicht EQUAL CARE einen zentralen Meilenstein und zeigt, dass sich komplexe regulatorische Texte zuverl\u00e4ssig aufbereiten, sodass die Information f\u00fcr Menschen und Maschinen zug\u00e4nglich ist. (Webseite zum Registry zu finden unter: https:\/\/registry.equal-care.org\/)
Im Rahmen der ersten Projektphase wurden 170 Wirkstoffe (INNs) <\/strong>aus unterschiedlichen therapeutischen Bereichen systematisch analysiert. Der Datensatz umfasst unter anderem Wirkstoffe aus der Kardiologie, Neurologie, Onkologie, Stoffwechselmedizin, Pneumologie und Immunologie sowie ausgew\u00e4hlte Indikationsgebiete. <\/p>\n\n\n\nWarum ein Evidenz-Register notwendig ist <\/strong><\/p>\n\n\n\nGeschlechtersensible Medizin gewinnt weltweit an Bedeutung, da biologische Unterschiede zwischen Patientinnen und Patienten die Wirksamkeit, Sicherheit und Dosierung von Arzneimitteln beeinflussen k\u00f6nnen. Dennoch fehlt es in Forschung, Versorgung und Regulierung an einer klar strukturierten, systematisch zug\u00e4nglichen Darstellung dieser Informationen.
\u201eGeschlechtsrelevante Hinweise liegen heute in unterschiedlichen Abschnitten verschiedener Dokumente vor, und ihre Formulierungen variieren je nach Wirkstoffklasse und Dokumenttyp. Eine einheitliche Struktur existiert bislang nicht. Genau hier setzen wir an\u201c, erkl\u00e4rt Thao Nguyen<\/strong>, CEO und Gr\u00fcnderin von EQUAL CARE. \u201eUnser Evidenz-Register schafft hier erstmals eine technisch konsistente Grundlage, um diese Informationen systematisch aufzufinden und vergleichbar zu machen.\u201c
W\u00e4hrend der Verarbeitung der 170 Wirkstoffe wurden unterschiedliche Dokumentformate, Terminologien und Sprachmuster identifiziert. Diese Vielfalt stellt ein wertvolles Trainingsumfeld dar und erm\u00f6glicht es, die Modelle f\u00fcr Klassifikation, Mustererkennung und semantische Strukturierung weiter zu verfeinern und auf einen gr\u00f6\u00dferen Datensatz anzuwenden.
Durch die Analyse k\u00f6nnen diese klinischen Studien erstmals in ein einheitliches, maschinenlesbares Format \u00fcberf\u00fchrt werden. Das Register dient dabei nicht <\/strong>der klinischen Bewertung, 2 EQUAL CARE AG <\/strong>Dammstr.16, CH-6300 Zug, Switzerland info@equal-care.org www.equal-care.org Risikoabsch\u00e4tzung oder Therapieempfehlung. Es bildet eine technische Infrastruktur, die vorhandene Evidenzen transparent, vergleichbar und strukturiert zug\u00e4nglich macht. <\/p>\n\n\n\nWarum dieses Thema jetzt besonders dringlich ist <\/strong><\/p>\n\n\n\nObwohl geschlechtsrelevante Unterschiede in Diagnostik, Therapie und Vertr\u00e4glichkeit wissenschaftlich beschrieben sind, sind diese Informationen im klinischen Alltag oft schwer auffindbar oder nicht systematisch aufbereitet. Leitlinien enthalten bislang nur begrenzt geschlechterspezifische Angaben und viele relevante Daten sind \u00fcber zahlreiche Dokumente verteilt.
\u201eViele Informationen, die f\u00fcr eine geschlechtersensible Medizin wichtig sind, liegen bereits vor, aber nicht in einer Form, die eine systematische Analyse erlaubt\u201c, sagt Dr. Simone Braun<\/strong>, \u00c4rztin und Gr\u00fcnderin von EQUAL CARE. \u201eMit dem Evidenz-Register schaffen wir erstmals eine technische Grundlage, auf der datenbasierte Vergleiche, Hypothesen und weiterf\u00fchrende Analysen aufgebaut werden k\u00f6nnen.\u201c
Weitere Wirkstoffe aus zus\u00e4tzlichen Fachgebieten folgen zeitnah. Perspektivisch flie\u00dfen neben Zulassungsstudien auch Post-Marketing-Daten und andere hochwertige Evidenzquellen ein. So entsteht schrittweise ein umfassendes, klinisch relevantes Fundament f\u00fcr geschlechtersensible Diagnostik und Therapie.
Durch regulatorische Entwicklungen wie den EU AI Act und den European Health Data Space steigt zudem der Bedarf an standardisierten, transparenten Datenstrukturen; ein Bereich, in dem EQUAL CARE eine notwendige L\u00fccke schlie\u00dft. <\/p>\n\n\n\n\u00dcber EQUAL CARE <\/strong>
EQUAL CARE ist ein von Thao Nguyen, Dr. Simone Braun und Ioana Freise gegr\u00fcndetes Unternehmen mit Standorten in der Schweiz und Deutschland, das technische Grundlagen f\u00fcr eine geschlechtersensible Gesundheitsversorgung entwickelt. Die Gr\u00fcnderinnen vereinen Expertise aus Medizin, Datenanalyse, Technologie und Gesundheitsregulierung und arbeiten daran, vorhandene medizinische Informationen strukturiert und transparent zug\u00e4nglich zu machen. Auf dieser Basis unterst\u00fctzt EQUAL CARE pr\u00e4zisere Forschung, digitale Gesundheitsl\u00f6sungen und eine wissenschaftlich fundierte, geschlechtersensible Medizin. <\/p>\n\n\n\nPressekontakt <\/strong>
Ioana Freise
E-Mail: mail@equal-care.org
Web: www.equal-care.org <\/p>\n\n\n\n<\/p>\n","protected":false},"excerpt":{"rendered":"
Zug, 15 December 2025 – German version below EQUAL CARE, a data- and AI-driven health-tech company, today introduces an evidence register that structures publicly available clinical study information and makes it searchable regarding sex- and gender-relevant aspects.With the analysis of the first 170 active substances (INNs), EQUAL CARE reaches a key milestone and demonstrates that… Read More »EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"_ti_tpc_template_sync":false,"_ti_tpc_template_id":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-468","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nEQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed - EQUAL CARE BLOG<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed - EQUAL CARE BLOG\" \/>\n<meta property=\"og:description\" content=\"Zug, 15 December 2025 – German version below EQUAL CARE, a data- and AI-driven health-tech company, today introduces an evidence register that structures publicly available clinical study information and makes it searchable regarding sex- and gender-relevant aspects.With the analysis of the first 170 active substances (INNs), EQUAL CARE reaches a key milestone and demonstrates that… Read More »EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/\" \/>\n<meta property=\"og:site_name\" content=\"EQUAL CARE BLOG\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-15T07:48:01+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-16T13:35:29+00:00\" \/>\n<meta name=\"author\" content=\"Thao Nguyen\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Thao Nguyen\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/\",\"url\":\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/\",\"name\":\"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed - EQUAL CARE BLOG\",\"isPartOf\":{\"@id\":\"https:\/\/www.equal-care.org\/blog\/#website\"},\"datePublished\":\"2025-12-15T07:48:01+00:00\",\"dateModified\":\"2025-12-16T13:35:29+00:00\",\"author\":{\"@id\":\"https:\/\/www.equal-care.org\/blog\/#\/schema\/person\/c033144e921c05c0d0e5f6635354da72\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.equal-care.org\/blog\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.equal-care.org\/blog\/#website\",\"url\":\"https:\/\/www.equal-care.org\/blog\/\",\"name\":\"EQUAL CARE BLOG\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.equal-care.org\/blog\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.equal-care.org\/blog\/#\/schema\/person\/c033144e921c05c0d0e5f6635354da72\",\"name\":\"Thao Nguyen\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.equal-care.org\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/77b535824bdaa5f422a1cfa8ec7cf18acbcee0887920a85e4ed5d078dfeef164?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/77b535824bdaa5f422a1cfa8ec7cf18acbcee0887920a85e4ed5d078dfeef164?s=96&d=mm&r=g\",\"caption\":\"Thao Nguyen\"},\"url\":\"https:\/\/www.equal-care.org\/blog\/author\/thao\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed - EQUAL CARE BLOG","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/","og_locale":"en_US","og_type":"article","og_title":"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed - EQUAL CARE BLOG","og_description":"Zug, 15 December 2025 – German version below EQUAL CARE, a data- and AI-driven health-tech company, today introduces an evidence register that structures publicly available clinical study information and makes it searchable regarding sex- and gender-relevant aspects.With the analysis of the first 170 active substances (INNs), EQUAL CARE reaches a key milestone and demonstrates that… Read More »EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed","og_url":"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/","og_site_name":"EQUAL CARE BLOG","article_published_time":"2025-12-15T07:48:01+00:00","article_modified_time":"2025-12-16T13:35:29+00:00","author":"Thao Nguyen","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Thao Nguyen","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/","url":"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/","name":"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed - EQUAL CARE BLOG","isPartOf":{"@id":"https:\/\/www.equal-care.org\/blog\/#website"},"datePublished":"2025-12-15T07:48:01+00:00","dateModified":"2025-12-16T13:35:29+00:00","author":{"@id":"https:\/\/www.equal-care.org\/blog\/#\/schema\/person\/c033144e921c05c0d0e5f6635354da72"},"breadcrumb":{"@id":"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.equal-care.org\/blog\/2025\/12\/equal-care-launches-first-evidence-register-for-sex-and-gender-informed-medicine-170-active-substances-analysed\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.equal-care.org\/blog\/"},{"@type":"ListItem","position":2,"name":"EQUAL CARE launches first publicly available evidence register for sex- and gender-informed medicine: First 170 active substances analysed"}]},{"@type":"WebSite","@id":"https:\/\/www.equal-care.org\/blog\/#website","url":"https:\/\/www.equal-care.org\/blog\/","name":"EQUAL CARE BLOG","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.equal-care.org\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.equal-care.org\/blog\/#\/schema\/person\/c033144e921c05c0d0e5f6635354da72","name":"Thao Nguyen","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.equal-care.org\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/77b535824bdaa5f422a1cfa8ec7cf18acbcee0887920a85e4ed5d078dfeef164?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/77b535824bdaa5f422a1cfa8ec7cf18acbcee0887920a85e4ed5d078dfeef164?s=96&d=mm&r=g","caption":"Thao Nguyen"},"url":"https:\/\/www.equal-care.org\/blog\/author\/thao\/"}]}},"_links":{"self":[{"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/posts\/468","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/comments?post=468"}],"version-history":[{"count":9,"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/posts\/468\/revisions"}],"predecessor-version":[{"id":483,"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/posts\/468\/revisions\/483"}],"wp:attachment":[{"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/media?parent=468"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/categories?post=468"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.equal-care.org\/blog\/wp-json\/wp\/v2\/tags?post=468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}